Biophotonics is the science of harnessing light to image, detect and manipulate biological materials.

The products developed by Guided Therapeutics are derived from our biophotonic technology platform.  We use light to scan tissue and detect chemical and structural changes at the cellular level.  These changes from normal conditions can indicate the early stages of cancer. Unlike most conventional cancer diagnostics, our technology is designed to provide a result immediately after the scan and with no painful biopsy tissue sample to be sent to the laboratory.

The scanning technology can see below the surface of the tissue to detect disease before it may be visible to conventional testing methods such as cytology or pathology.

Biophotonics can detect disease before it becomes obvious on the surface.

Biophotonics can detect disease before it becomes obvious on the surface.

Biophotonics is used in medicine to study tissue and blood at the macro (large-scale) and micro (very small scale) level to detect, diagnose and treat diseases in ways that are non-invasive to the body.

The LuViva® Advanced Cervical Scan uses reflectance and fluorescence spectroscopy to detect both physical and chemical changes in tissue that are markers of cervical disease.



Reflectance spectroscopy measures the color and intensity of reflected light and can be used to determine if structural changes are taking place in tissue. In the case of LuViva, structural changes that effect light reflectance are: epithelial thickening, nuclear size and content and increased blood flow.




Fluorescence spectroscopy measures the wavelength of light that is re-emitted from an object that has been illuminated. It is used to determine the presence and concentration of certain chemical markers present in tissue. In the case of LuViva, fluorescent markers present that may indicate the early stages of cancer are: tryptophan, flavins and/or collagen.

More information on Biophotonics

Optical Imaging of the Cervix

Tissue Optics